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133 - 155
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The distribution of 5 S rRNA sequences in phenetic hyperspace is examined and compared with an evolutionary tree constructed by weighted pairwise grouping, a phenetic clustering procedure. A factorial correction for unequal evolutionary rates is proposed. Such a correction is shown to be a necessary, but not a sufficient condition for a valid phylogenetic reconstruction. The resolving power of the clustering procedure is shown to have an optimum between 15% and 40% sequence dissimilarity for the eukaryotes and between 5% and 30% for the eubacteria. The probability of including deviant clusters increases if these limits are exceeded. On the basis of paleontological evidence the evolutionary rates of 5 S rRNAs derived from eukaryotes and eubacteria is determined to be 0,26 x 10^-9 and 0,15 x 10^-9 fixed mutations x nucleotide^-1 x year^-1 respectively. Implications for the archaebacterial state are discussed.
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